Women carrying a genetic defect that makes it hard for them to metabolize Folic acid are at a higher risk for giving birth to a baby with Down syndrome.
That’s the finding in a study by researchers at the U.S. Food and Drug Administration that is published in the Sept. 28 issue of American Journal of Clinical Nutrition.
Researchers found the gene MTHFR plays a role in how chromosomes separate during ovulation and how the body processes folic acid. Normally, an egg and a sperm each carry 23 chromosomes, but if either carries an extra chromosome, that leads to Down syndrome. If the egg carries the extra chromosome, that problem usually occurs during ovulation. |
 |
|
Folic acid is found in leafy green vegetables, beans, tuna and eggs. Government has ordered that pasta, cereal and flour to be fortified with folic acid. |
Health experts recommend all women of childbearing age get at least 400 micrograms of folic acid daily because it helps prevent a variety of birth defects. However, women do not reap the benefits of folic acid after conception, so they should begin taking supplements before becoming pregnant. |
|