MRI may diagnose
Alzheimer's disease
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Scientist in Japan have found
out a method to detect the amyloid plaques in the brain of living mice
using MRI scanners with the help of a new Flourine tracer. Currently the
standard way to detect the amyloid plaques of this disease is by autopsy
i.e. after death. This raises the possibility that people without overt
symptoms may be diagnosed and treated before the disease has manifested
itself.
Amyloid plaques are insoluble
proteins clumps in the brain which form early in Alzheimer's disease
and can precede by many years the actual development of dementia. If the
disease can be identified before the irreversible neuron loss has taken
place in the brain and in a stage when the person is asymptomatic, there
is possibility of treating this disease or slowing its progression.
This new tracer has been
developed by Takaomi Saido and his team at Riken Brain Science
Institute in Wako, Japan. This non-toxic tracer attaches itself to
the amyloid plaques in the brain and can be detected by regular MRI. The
tracer is made from a form of fluorine that is a common additive in
drinking water.
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